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These anatomical studies were followed
2024-03-18

These anatomical studies were followed by the first functional MRI studies of auditory processing in songbirds that were performed in starlings (Van Meir et al., 2005; De Groof et al., 2017; De Groof et al., 2013b) and in zebra finches (Boumans et al., 2008a; Boumans et al., 2007; Boumans et al., 20
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The current findings proved that
2024-03-18

The current findings proved that citral treatment induced mitochondrial-mediated apoptotic cell death in both HCT116 and HT29 through the p53 and ROS. As such, citral promoted apoptosis as evident by the externalization of PS and dissipation of Δψm at 24h of treatment in HCT116 and HT29 cells. These
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br Conflict of interest br Acknowledgments
2024-03-18

Conflict of interest Acknowledgments This work was financially supported by the Fund Project of Sichuan Provincial Department of Education (16ZB0053), the Scientific Research Foundation of Sichuan Agricultural University (No. 06021400) and the China Postdoctoral Science Foundation (No. 2015M58
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Although the interactions of PhLP with G and
2024-03-18

Although the interactions of PhLP with Gβγ and its other partners have been convincingly documented through in vitro studies, it is not clear how PhLP controls p-nitro-Cyclic Pifithrin-α signaling in vivo. C. elegans provides a powerful genetic model to analyze Phosducin function and study its inte
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SR 2595 receptor Sorafenib was the first small RTK inhibitor
2024-03-18

Sorafenib was the first small RTK inhibitor drug to be developed and was initially approved against renal cell carcinoma, then against hepatocellular carcinoma (HCC) and more recently for differentiated thyroid treatment [111]. Sunitinib soon followed, being approved for gastrointestinal stromal tum
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br Introduction Hepatocellular carcinoma HCC is the
2024-03-18

Introduction Hepatocellular carcinoma (HCC) is the third-leading cause of cancer-related death worldwide and accounts for 70–85% of all liver cancer diagnoses [1]. In East and South-East Asia, the occurrence of HCC and the related number of fatalities have gradually increased in recent decades [2
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br Concluding remarks Enhanced membrane binding upon calcium
2024-03-18

Concluding remarks Enhanced membrane binding upon calcium stimulation in wst-1 synthesis suggests a pre-requisite step that involves a conformational change in LOX. This might facilitate it to tether to the membrane and regulate enzyme activity. The calcium binding loops and the putative active s
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Outro grupo de trabalho analisou pares de g meos dinamarques
2024-03-18

Outro grupo de trabalho analisou 8.503 pares de gêmeos dinamarqueses de meia‐idade (nos Wiskostatin de cognição comparados com os que não sofreram qualquer intervenção, no entanto os autores consideram a diferença como um efeito de tamanho negligenciável. Na análise intrapares o gêmeo exposto à ciru
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These mutations induce the gene
2024-03-18

These mutations induce the gene auto-activation in 10–40% of adenocarcinomas, triggering the EGFR-signaling pathway in the absence of ligand. That leads to an uncontrolled acceleration of cell proliferation, survival and anti-apoptotic signals (Couraud et al., 2012). The frequency of these mutations
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br Conclusion br Conflict of interest
2024-03-18

Conclusion Conflict of interest Acknowledgements Introduction Human salivary aldehyde dehydrogenase (hsALDH) (E.C. 1.2.1.5) is the first line of defence against toxic aldehydes in the oral cavity. HsALDH is primarily a dimeric, class 3 ALDH (ALDH3A1) specific for aromatic and long/medium
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In our previous study adiponectin system genes and
2024-03-18

In our previous study, adiponectin system (genes and proteins) expression in the porcine endometrium and myometrium was observed on Days 2 to 3, 10 to 12, 14 to 16, and 17 to 19 of the estrous cycle [23]. Adiponectin receptors expression (mRNA) in the porcine endometrium was described by Lord et al.
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The reduced IFN production seen with BPAL
2024-03-18

The reduced IFNγ production seen with BPAL10-primed splenocytes could potentially be attributed to the impaired intracellular survival of B. pertussis, thereby leading to a weakened induction of cell-mediated immunity. Earlier studies have suggested an antimicrobial role of IFNγ in mediating the eli
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By promoting bundling and processive elongation
2024-03-16

By promoting bundling and processive elongation of 4EGI-1 filaments and inhibiting association of capping protein with filament barbed ends, Ena/VASP family proteins contribute to the dynamics of lamellipodia and filopodia [41] and maintenance of focal adhesions and tight junctions [42, 43]. Accord
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br Results and discussion The morphology and structure
2024-03-16

Results and discussion The morphology and structure of isrib samples were observed using an SEM, as shown in Fig. 1. The length and thickness of the actin filaments were regulated with ABPs to mimic the various actins observed in cells. We prepared three types of F-actin with or without gelsolin
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In this study we obtained the absorbance and photoluminescen
2024-03-16

In this study, we obtained the absorbance and photoluminescence (PL) of Ac-YVAD-CHO synthesis polymerized with various types of actin-binding proteins in order to probe the actin structures in situ without labeling. Both optical measurements have been useful in examining biomaterials such as DNA and
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